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Copper Peptides
In the snail's body tissues, glycosaminoglycans (GAGs) are primarily located inside granules and in the shell, and are secreted onto the surface as a mucous material. Snail glycosaminoglycan tightly binds divalent copper cations (Cu 2+) and form copper peptides , with reportedly have skin regeneration properties. The concentration of copper in the snail secretions is notable, but copper peptides have been shown to be active in nanomolar amounts.
Copper-induced vascular endothelial growth factor expression and wound healing. Sen CK, Khanna S, Venojarvi M, Trikha P, Ellison EC, Hunt TK, Roy S. 2002 May;282(5):H1821-7. http://ajpheart.physiology.org/cgi/ingredient/full/282/5/H1821
Laboratory of Molecular Medicine, Department of Surgery, 512 Davis Heart & Lung Research Institute, The Ohio State University Medical Center, Columbus, Ohio 43210, USA.
Angiogenesis - the growth of new blood vessels - plays a central role in wound healing. Among many known growth factors, vascular endothelial growth factor (VEGF) is believed to be the most prevalent, efficacious, and long-term signal that is known to stimulate angiogenesis in wounds. Whereas a direct role of copper to facilitate angiogenesis has been evident two decades ago, the specific targets of copper action remained unclear. This report presents first evidence showing that inducible VEGF expression is sensitive to copper and that the angiogenic potential of copper may be harnessed to accelerate dermal wound contraction and closure. At physiologically relevant concentrations, copper sulfate induced VEGF expression in primary as well as transformed human keratinocytes. Copper shared some of the pathways utilized by hypoxia to regulate VEGF expression. Topical copper sulfate accelerated closure of excisional murine dermal wound allowed to heal by secondary intention. Copper-sensitive pathways regulate key mediators of wound healing such as angiogenesis and extracellular matrix remodeling. Copper-based therapeutics represents a feasible approach to promote dermal wound healing.
Certain types of copper peptide complexes possess both tissue protection and repair properties. Cu has protective and regenerative actions on several organ systems including skin, hair follicles, bone, gastric mucosa and intestinal linings. These types of copper complexes are increasingly used in cosmetic skin and hair care products and after dermatological skin renewal procedures, such as chemical peels, laser resurfacing and dermabrasion, to improve post-treatment skin recovery .
Aging reversal of skin
The greatest interest in copper peptides is in the area of reversing the effects of human ageing and ultraviolet damage on human skin. During ageing, skin becomes thinner and tends to accumulate various skin lesions and imperfections. The dermis and epidermis thin and the subcutaneous fat cells diminish in number.
A number of studies have found that the application of copper peptide creams to the human skin is more effective in promoting collagen development than retinoic acid or vitamin C. It also increase s the thickness of the epidermis and dermis, increases skin elasticity, reduces wrinkles and removes skin imperfections such as blotchiness and sun damage marks.
GLYCOBALM for Acne Treatment
A gentle yet powerful solution for acne breakouts and even stubborn acne cysts that have not been amenable to other treatments
This acne cream yields what no other natural acne product does for recurrent stubborn acne and acne cysts because of the synergistic benefit of combining our biological serum with the most potent botanicals:
a) Inca Inchi Oil the richest vegetable oil in Omega-3 fatty acids. A powerful anti-inflammatory and with the ability to correct the deficit of linoleic acid in hair follicles which is a trigger of immoderate inflammatory reactions from our immune system. The oil is also a factor that reduces sebum output;
b) Helix Aspersa Müller Glycoconjugates, the miraculous serum, from a living creature with skin similar to human skin who never suffers from skin infections and acts as an effective adaptogen, anti-inflammatory, antioxidant, trigger of skin repair and skin regeneration, and enzyme dissolver of blocked pores;
c) Licorice Root Extract (*) an antimicrobial with potent activity against acne bacteria, anti-inflammatory, anti-irritant, antioxidant, and an inhibitor of sebum production;
d) Alpine Willow herb extract (Epilobium Fleischeri) a botanical source of keratolytic salicylic acid in a natural form, and an antimicrobial;
e) Essential oil from the roots of Coleus Forskohlii with strong antimicrobial activity and a strong medicinal smell that you might not appreciate for about 20 minutes until it fades away.
The smell is a small price you pay for an "essential" component of BIOSKINFORTE for it activates many of your more than 10 million olfactory receptor neurones. But its nothing = "nada" when compared to the value you get: the strongest remedy that effectively heals and contains acne breakouts without any side effects on your body or skin. You always have the choice to behave as if you were a warrior and just use the product without previously messing with your nose inside the jar.
f) Hyaluronic Acid a glycosaminoglycan (also present in the snail serum) that deeply moisturizes the skin and restores the capacity of the skin to hold in water;
g) An extract from the fruit of black pepper which enhances the penetration of the active ingredients.
Apply a little of this acne cream twice a day on all the area affected by acne cysts or stubborn pimples (whole face, chest or back).
Made in the USA. One Month Supply 50 grams = 1.76 oz
$69.98
(*) A New Dermatological Availability of the Flavonoid Fraction from Licorice Roots-Effect on Acne
Journal of Society Cosmetic Chemists Japan, VOL.37; NO.3; PAGE. 179-186(2003) Authors: Kambara Toshimitsua, Zhou Y, Kawashima Yoshihitoa, Kishida Naokoa, Mizutani Kenjia, Ikeda Takaoa, Kameyama Koichirob.
a) Research Center, Maruzen Pharmaceuticals Co., Ltd., 1089-8 Sagata, Shin-ichi, Fukuyama, 729-3102 Hiroshima, Japan. b) Aoyama Dermatological Clinic, dr@aoyamahihuka.com 5-1-3 Aoyama 8F Minato-ku Tokyo 107 Japan. Link: Licorice Roots-Effect on Acne
Abstract: Licochalcone-A, Polyol Soluble Licorice Extract P-U (now in the market as Licochalcone LR-15), prepared from the roots of Glycyrrhiza Inflata Batalin shows several activities such as inhibitory actions of testosterone 5 ALPHA-reductase, lipase and phospholipase A2, as well as androgen receptor antagonist, antimicrobial and SOD-like antioxidant actions, which relate to skin care, especially the suppression of acne formation and development. On basis of this evidence, a trial with acne patients was carried out and the efficacy of the extract was demonstrated clinically.
Check also our specialty natural skin care products: BIO SKIN REJUVENATION to get rid of brown sun spots, BIOSKINEXFOL for the treatment of old acne scars, and BIO STRETCH MARK CREAM for the prevention and treatment of new stretch marks.
Toll Free USA & Canada
BIOCUTIS skin treatment products
GLYCOBALM 
Strongest natural acne treatment cream or balm, based on the natural glycoconjugates compound produced by snails to function as its powerful immune modulator and skin regeneration trigger. Removes dead cells, unclogs sebum canals and dissolves scar tissues by enzymatic hydrolysis, without peeling. Promotes the secretion of antimicrobial peptides on the skin surface and those keep bacteria at bay and control acne. Boosts the production of glycosaminoglycans, the molecules that hold in water in the dermis, thus truly moisturizing the skin from within. Communicates to your immune system that you are being taken care of and can moderate an otherwise extreme inflammatory reaction that may end up destroying healthy skin cells together with bacteria and sebum that has turned into a foreign matter. 50 gram (1.76 oz) $69.98
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BIOSKINCARE
A natural skin care balm that triggers the regeneration of damaged cells, deeply moisturizes and replenishes the lipid barrier of the skin while repairing skin lesions, preventing and dissolving scars left behing by acne inflammation, and scarring from accidental injuries and surgery; stretch marks; abnormal scars of the types hypertrophic and keloid; keratois pilaris plugs, actinic keratosis scales, dermatitis, psoriasis scales and all types of skin blemishes. 50 gram (1.76 oz) jar = $59.98 and for two or more 20% discount.
BIOSKINEXFOL™
A home microdermabrasion cream with high quality microcrystals, the same that professionals use to break-down and polish or resurface hard, rough and old scar tissues. Allows for a deeper penetration of our biological skin moisturizing and regeneration complex that is combined with the crystals in the microdermabrasion cream. 120 gram (4 oz) jar = $79
BIO STRETCH MARK CREAM™
Helps to prevent stretch marks, strengthen fragile skin, firm sagging breasts and body areas and reduce cellulite. It also works for new formed stretch marks and scars, while BIOSKINEXFOL is recommended for old, rough and raised marks. This product is similar to BIOACNECARE, although in an economic tottle, with 6 oz. For use preferably on the body, not on the face, for it contains a higher concentration of the biological complex which results in an invisible film that retains in moisture by occluding the area where it is applied and could feel a little tacky on the face depending on how oily is your facial skin. 6 oz (180g) tottle = $118.50
BIO SKIN REJUVENATION™
Same cream base with intercellular communicating ingredients and enzymes as in BIOACNECARE to "digest" or dissolve blemishes, speed skin turnover, moisturize and tighten skin, plus two added ingredients: a natural pigment reducer and a human growth factor peptide, derived from the melanocyte-stimulating-hormone that blocks melanin synthesis, and inhibits the formation of unwanted pigmentation, allowing control over skin tone and brown spots. Leaves skin bright and refreshed! 50 gram (1.76 oz) jar = $69.98
Customer's Testimonials and Tips:
It heals my acne. This formula is a 'miracle'. It has performed miracles, that my doctor could not, with several prescriptions. I have only used for 1.5 months, and already, I am 'looking healed and gooood', which makes me feel good!!! Thanks again! K. In Hou. Texas. USA
I have seen more of a result, with this product than any others I have tried for acne scars. My scars are not as deep as they were and my face is smoother looking, it is working great on my small crow's feet too, by my eyes...they look hardly noticeable now, thank you for this wonderful product! Violet Wood. Florida, US
